Hormone replacement therapy (HRT) can have both positive and negative effects on migraines, depending on the individual and the specific type of HRT used. For women considering HRT who have migraines, they should discuss with their provider their risks.
Hormone replacement therapy (HRT) can have both positive and negative effects on migraines, depending on the individual and the specific type of HRT used. For women without aura, HRT might help alleviate menstrual migraine symptoms by reducing hormonal fluctuations. However, for those with aura, combination oral contraceptives are generally not recommended due to the increased risk of stroke.
### Key Points:
- For women without aura, HRT can help minimize menstrual migraine symptoms by reducing hormonal fluctuations[1][2][3].
- Combination oral contraceptives can increase the risk of stroke for women with aura, so it is generally not recommended[1][3][5].
- Using the lowest doses of transdermal estrogen necessary to control vasomotor symptoms can minimize the risk of unwanted side effects[2].
- Cyclical progestogens can have an adverse effect on migraines, so continuous progestogens are preferred[2].
- Non-hormonal options for both conditions are limited, but there is evidence of efficacy for escitalopram and venlafaxine[2].
- Lifestyle factors such as diet, hydration, sleep, stress management, and vitamins can also play a significant role in managing migraines[5].
Migraine, menopause and hormone replacement therapy - PubMed
Perimenopause marks a period of increased migraine prevalence in women and many women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating estrogen levels with evidence to support estrogen withdrawal as a trigger of menst
Considerations for hormonal therapy in migraine patients: a critical review of current practice
Migraine, a neurovascular headache disorder, is a leading cause of disability worldwide. Within the multifaceted pathophysiology of migraine, hormonal fluctuations play an evident triggering and exacerbating role, pointing toward the need for identif